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    科学研究

    2020

    1. gem-Difluoromethylene Alkyne-Enabled Diverse C-H Functionalization and Application to the on-DNA Synthesis of Difluorinated Isocoumarins. Gao, Hui(3,4,5);Lin, Shuang(3,4,5);Zhang, Shuning(1,2);Chen, Weijie(3,4,5);Liu, Xiamen(3,4,5);Yang, Guang(1);Richard A. Lerner(6);Xu, Hongtao(1);Zhou, Zhi(3,4,5);Yi, Wei(3,4,5). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020. DOI:. 10.1002/anie.202013052

    2. Coarse-Grained Parameters for Divalent Cations within the SIRAH Force Field. Klein, Florencia(1);Caceres, Daniela(2,3);Carrasco, Monica A.(2);Carlos Tapia, Juan(2);Caballero, Julio(3);Alzate-Morales, Jans(3);Pantano, Sergio(1,4). JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2020. DOI:. 10.1021/acs.jcim.0c00160

    3. Efficacy of early prone position for COVID-19 patients with severe hypoxia: a single-center prospective cohort study. Zang, Xuefeng(1);Wang, Qian(2);Zhou, Hua(3);Liu, Sanhong(4,5);Xue, Xinying(6,7). INTENSIVE CARE MEDICINE. 2020. DOI:. 10.1007/s00134-020-06182-4

    4. Tripterygium glycoside fraction n2 ameliorates adriamycin-induced nephrotic syndrome in rats by suppressing apoptosis. Wang, Xiao-wan(1);Tian, Rui-min(2);Yang, Yi-qi(1);Wang, Kai(1);Li, En-nian(1);Han, Xiao-dong(1);Bao, Kun(2);Mao, Wei(1);Xu, Hong-tao(3);Liu, Bo(1,4);Xu, Peng(2). JOURNAL OF ETHNOPHARMACOLOGY. 2020. DOI:. 10.1016/j.jep.2020.112789

    5. Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products. Xie, Jia(1);Wang, Shuyue(2,3,4,5);Ma, Peixiang(2);Ma, Fei(1,2,5);Li, Jie(2,3,4);Wang, Wei(2);Lu, Fengping(2);Xiong, Huan(2);Gu, Yuang(2,3,4,5);Zhang, Shuning(2,3,4,5);Xu, Hongtao(2);Yang, Guang(2);Lerner, Richard A.(1). ISCIENCE. 2020. DOI:. 10.1016/j.isci.2020.101197

    6. Intravital three-dimensional bioprinting. Urciuolo, Anna(1,2,3);Poli, Ilaria(4);Brandolino, Luca(1,2);Raffa, Paolo(2,3);Scattolini, Valentina(2,3);Laterza, Cecilia(1,2);Giobbe, Giovanni G.(5);Zambaiti, Elisa(3);Selmin, Giulia(5);Magnussen, Michael(5);Brigo, Laura(2);De Coppi, Paolo(5,6);Salmaso, Stefano(7);Giomo, Monica(1);Elvassore, Nicola(1,2,5,8). NATURE BIOMEDICAL ENGINEERING. 2020. DOI:. 10.1038/s41551-020-0568-z

    7. Identification of exosomal miRNAs as diagnostic biomarkers for cholangiocarcinoma and gallbladder carcinoma. Xue, Xin-ying(1,2,3);Liu, Yu-xia(4);Wang, Chen(5);Gu, Xin-jin(6);Xue, Zhi-qiang(7);Zang, Xue-lei(8);Ma, Xi-dong(3);Deng, Hui(1);Liu, Rong(6);Pan, Lei(1);Liu, San-hong(5). SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2020. DOI:. 10.1038/s41392-020-0162-6

    8. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Zhang, Xiaotian(1,4);Jeong, Mira(1,2);Huang, Xingfan(3,7,8,17);Wang, Xue Qing(4);Wang, Xinyu(5);Zhou, Wanding(4);Shamim, Muhammad S.(3,6,7,8);Gore, Haley(4);Himadewi, Pamela(4);Liu, Yushuai(4);Bochkov, Ivan D.(3,9);Reyes, Jaime(1,2,9);Doty, Madison(10);Huang, Yung-Hsin(1,2,11);Jung, Haiyoung(1,2,12);Heikamp, Emily(1,2,13);Aiden, Aviva Presser(3,11,13);Li, Wei(14,15);Su, Jianzhong(5);Aiden, Erez Lieberman(3,7,8,9,16);Goodell, Margaret A.(1,2,9,13,15). MOLECULAR CELL. 2020. DOI:. 10.1016/j.molcel.2020.04.018

    9. Engineering a 3D in vitro model of human skeletal muscle at the single fiber scale. Urciuolo, Anna(1,2,3);Serena, Elena(1,2);Ghua, Rusha(4);Zatti, Susi(1,2);Giomo, Monica(1,2);Mattei, Nicolo(1,2);Vetralla, Massimo(1,2);Selmin, Giulia(1);Luni, Camilla(5);Vitulo, Nicola(6);Valle, Giorgio(4);Vitiello, Libero(4,7);Elvassore, Nicola(1,2,5,8). PLOS ONE. 2020. DOI:. 10.1371/journal.pone.0232081

    10. Exosomal piRNA profiling revealed unique circulating piRNA signatures of cholangiocarcinoma and gallbladder carcinoma. Gu, Xinjin(1);Wan, Chen(2);Deng, Hui(3);Qing, Chong(3);Liu, Rong(1);Liu, Sanhong(2);Xue, Xinying(3). ACTA BIOCHIMICA ET BIOPHYSICA SINICA. 2020. DOI:. 10.1093/abbs/gmaa028

    11. Establishment of SIAISi002-A, an induced pluripotent stem cell (iPSC) line from 39-year old healthy female donor with a family history of Alzheimer's disease (AD) and two copies of APOE4 gene. Yan, Yi(1,2);Qiu, Yinghui(1,2);Zhao, Aonan(1,2);Zhao, Jian(3,4);Wang, Ying(3);Deng, Yulei(1,2). STEM CELL RESEARCH. 2020. DOI:. 10.1016/j.scr.2020.101792

    12. Bcl-3 promotes Wnt signaling by maintaining the acetylation of beta-catenin at lysine 49 in colorectal cancer. Chen, Xi(1);Wang, Chen(1,2);Jiang, Yuhang(1,3);Wang, Qi(1);Tao, Yu(1,3);Zhang, Haohao(1,3);Zhao, Yongxu(1);Hu, Yiming(1,3);Li, Cuifeng(1,3);Ye, Deji(1);Liu, Dandan(1);Jiang, Wenxia(1);Chin, Eugene Y.(1);Chen, Sheng(4);Liu, Yongzhong(5);Wang, Mingliang(6);Liu, Sanhong(1,2);Zhang, Xiaoren(1,3). SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2020. DOI:. 10.1038/s41392-020-0138-6

    13. Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology. Hou, Wei(1,2);Liu, Bo(3,4);Xu, Hongtao(5). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.ejmech.2020.112081

    14. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Xue, Xinying(1,2);Wang, Chen(3);Xue, Zhiqiang(4);Wen, Jiaxin(4);Han, Jun(5);Ma, Xidong(6);Zang, Xuelei(7);Deng, Hui(2);Guo, Rui(2);Asuquo, Idorenyin Polycarp(8);Qin, Chong(2);Wang, Haijiao(2);Gao, Quansheng(9);Liu, Sanhong(3);Wang, Jianxin(1). ACTA BIOCHIMICA ET BIOPHYSICA SINICA. 2020. DOI:. 10.1093/abbs/gmz164

    15. Establishment of SIAISi001-A, an induced pluripotent stem cell (iPSC) line from 66-year old mild cognitive impairment (MCI) with two copies of APOE4 gene. Yan, Yi(1,2);Qiu, Yinghui(1,2);Zhao, Aonan(1,2);Zhao, Jian(3);Wang, Ying(3);Deng, Yulei(1,2). STEM CELL RESEARCH. 2020. DOI:. 10.1016/j.scr.2020.101702

    16. ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. Wutz, Gordana(1);Ladurner, Rene(1,15);St Hilaire, Brian Glenn(2,3,4);Stocsits, Roman R.(1);Nagasaka, Kota(1);Pignard, Benoit(1);Sanborn, Adrian(2,5);Tang, Wen(1);Varnai, Csilla(6,7);Ivanov, Miroslav P.(1,16);Schoenfelder, Stefan(6,17);van der Lelij, Petra(1);Huang, Xingfan(2,8,9,10);Duernberger, Gerhard(11,18);Roitinger, Elisabeth(11);Mechtler, Karl(1,11);Davidson, Iain Finley(1);Fraser, Peter(6,12);Lieberman-Aiden, Erez(2,3,4,8,13,14);Peters, Jan-Michael(1). ELIFE. 2020. DOI:. 10.7554/eLife.52091

    17. Post-Translational Modifications at the Coarse-Grained Level with the SIRAH Force Field. Garay, Pablo G.(1);Barrera, Exequiel E.(1);Pantano, Sergio(1,2). JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2020. DOI:. 10.1021/acs.jcim.9b00900

    18. An ultra-stable cytoplasmic antibody engineered for in vivo applications. Kabayama, Hiroyuki(1,2);Takeuchi, Makoto(1);Tokushige, Naoko(1);Muramatsu, Shin-ichi(3,4);Kabayama, Miyuki(5);Fukuda, Mitsunori(6);Yamada, Yoshiyuki(1);Mikoshiba, Katsuhiko(1,7,8). NATURE COMMUNICATIONS. 2020. DOI:. 10.1038/s41467-019-13654-9

    19. Architecture of a SARS-CoV-2 mini replication and transcription complex. Yan, Liming(1);Zhang, Ying(2);Ge, Ji(2);Zheng, Litao(2);Gao, Yan(1,3,4);Wang, Tao(1);Jia, Zhihui(5);Wang, Haofeng(3,4);Huang, Yucen(1);Li, Mingyu(1);Wang, Quan(3,4);Rao, Zihe(1,2,3,4);Lou, Zhiyong(1). NATURE COMMUNICATIONS. 2020. DOI:. 10.1038/s41467-020-19770-1

    20. Automated design and optimization of multitarget schizophrenia drug candidates by deep learning. Tan, Xiaoqin(1,2);Jiang, Xiangrui(3);He, Yang(3);Zhong, Feisheng(1,2);Li, Xutong(1,2);Xiong, Zhaoping(1,4,5);Li, Zhaojun(1,6);Liu, Xiaohong(1,4,5);Cui, Chen(1,2);Zhao, Qingjie(3);Xie, Yuanchao(3);Yang, Feipu(3);Wu, Chunhui(3);Shen, Jingshan(3);Zheng, Mingyue(1,2);Wang, Zhen(3);Jiang, Hualiang(1,2,4,5). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.ejmech.2020.112572

    21. Potential treatment of COVID-19 by inhibitors of human dihydroorotate dehydrogenase. Xu, Yechun(1,2);Jiang, Hualiang(1,2,3,4). PROTEIN & CELL. 2020. DOI:. 10.1007/s13238-020-00769-9

    22. Beneficial effects exerted by hydroxychloroquine in treating COVID-19 patients via protecting multiple organs. Yu, Bo(1,2);Li, Chenze(1,2);Chen, Peng(1,2);Li, Jia(3);Jiang, Hualiang(3,4,5);Wang, Dao-Wen(1,2). SCIENCE CHINA-LIFE SCIENCES. 2020. DOI:. 10.1007/s11427-020-1782-1

    23. Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients. Su, Hai-xia(1,2);Yao, Sheng(2,3);Zhao, Wen-feng(1,4,5);Li, Min-jun(6);Liu, Jia(2,3);Shang, Wei-juan(7);Xie, Hang(1);Ke, Chang-qiang(3);Hu, Hang-chen(1,2);Gao, Mei-na(1,2);Yu, Kun-qian(1,2);Liu, Hong(2,3);Shen, Jing-shan(1,2);Tang, Wei(1,2);Zhang, Lei-ke(7);Xiao, Geng-fu(7);Ni, Li(8,9);Wang, Dao-wen(8,9);Zuo, Jian-ping(2,3);Jiang, Hua-liang(1,2,10,11);Bai, Fang(10,11);Wu, Yan(7);Ye, Yang(2,3,11);Xu, Ye-chun(1,2). ACTA PHARMACOLOGICA SINICA. 2020. DOI:. 10.1038/s41401-020-0483-6

    24. Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model. Zhao, Jihui(1,5);Cui, Rongrong(1,2);Wang, Lihao(1,6);Chen, Yingjia(1);Fu, Zunyun(1,2);Ding, Xiaoyu(1);Cui, Chen(1);Yang, Tianbiao(1);Li, Xutong(1);Xu, Yuan(1,7);Chen, Kaixian(1,2,3,4);Luo, Xiaomin(1);Jiang, Hualiang(1,2,3,4);Zheng, Mingyue(1,5). JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1021/acs.jmedchem.9b01895

    25. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Dai, Wenhao(1,2);Zhang, Bing(3,4);Jiang, Xia-Ming(5);Su, Haixia(1,6);Li, Jian(1,6);Zhao, Yao(3,4);Xie, Xiong(1,6);Jin, Zhenming(3,4);Peng, Jingjing(1,6);Liu, Fengjiang(3,4);Li, Chunpu(1,6);Li, You(8);Bai, Fang(3,4);Wang, Haofeng(3,4);Cheng, Xi(1);Cen, Xiaobo(8);Hu, Shulei(1);Yang, Xiuna(3,4);Wang, Jiang(1,6);Liu, Xiang(9);Xiao, Gengfu(5);Jiang, Hualiang(1,3,4,6);Rao, Zihe(3,4);Zhang, Lei-Ke(5);Xu, Yechun(1,6);Yang, Haitao(3,4);Liu, Hong(1,6,7). SCIENCE. 2020. DOI:. 10.1126/science.abb4489

    26. Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2). Zhang, Lu(1);Zhao, Yao(2,3,4);Gao, Ruogu(4,5);Li, Jun(3,4);Yang, Xiuna(3,4);Gao, Yan(9);Zhao, Wei(1,2);Gurcha, Sudagar S.;Veerapen, Natacha(10);Batt, Sarah M.;Besra, Kajelle Kaur;Xu, Wenqing(3,4);Bi, Lijun(7,8);Zhang, Xian'en(8);Guddat, Luke W.(11);Yang, Haitao(3,4);Wang, Quan(3,4,7,8);Besra, Gurdyal S.(10);Rao, Zihe(1,2,3,4,7,8,9). PROTEIN & CELL. 2020. DOI:. 10.1007/s13238-020-00726-6

    27. Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis. Uyhazi, Katherine E.(1);Yang, Yiying(1,2,3);Liu, Na(1);Qi, Hongying(1);Huang, Xiao A.(1);Mak, Winifred(1,4);Weatherbee, Scott D.(5);de Prisco, Nicola(6,7,8);Gennarino, Vincenzo A.(6,7,8,9);Song, Xiaoling(2);Lin, Haifan(1,2,3,4,5). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020. DOI:. 10.1073/pnas.1916471117

    28. Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Wang, Lin(1);Wu, Juehui(1,2);Li, Jun(3,4);Yang, Hua(1);Tang, Tianqi(2);Liang, Haijiao(1,2);Zuo, Mianyong(2);Wang, Jie(1);Liu, Haipeng(1,5);Liu, Feng(1);Chen, Jianxia(1,5);Liu, Zhonghua(1);Wang, Yang(2);Peng, Cheng(2);Wu, Xiangyang(2);Zheng, Ruijuan(1);Huang, Xiaochen(1);Ran, Yajun(3,4);Rao, Zihe(3,4,6,7,8,9);Ge, Baoxue(1,2,5). NATURE. 2020. DOI:. 10.1038/s41586-019-1915-7

    29. Meeting organometallic chemistry with drug discovery: C-H activation enabled discovery of a new ring system of 12H-Indazolo[2,1-a]cinnolin-12-ones with anti-proliferation activity. Zhang, Xiang(1);Bai, Ruisong(2,3);Xiong, Huan(4);Xu, Hongtao(4);Hou, Wei(2,3). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2020. DOI:. 10.1016/j.bmcl.2019.126916

    30. MeCas12a, a Highly Sensitive and Specific System for COVID-19 Detection. Ma, Peixiang(1);Meng, Qingzhou(2);Sun, Baoqing(3);Zhao, Bing(4);Dang, Lu(2);Zhong, Mingtian(5);Liu, Siyuan(6);Xu, Hongtao(1);Mei, Hong(1);Liu, Jia(1);Chi, Tian(6);Yang, Guang(1);Liu, Ming(3);Huang, Xingxu(6);Wang, Xinjie(1). ADVANCED SCIENCE. 2020. DOI:. 10.1002/advs.202001300

    31. PIWIL1 promotes gastric cancer via a piRNA-independent mechanism. Shi, Shuo(1);Yang, Zhen-Zhen(1);Liu, Sanhong(1);Yang, Fan(1);Lin, Haifan(2,3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020. DOI:. 10.1073/pnas.2008724117

    32. Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations. He, Di(1,2);Wang, Di(2);Lu, Ping(3);Yang, Nan(4);Xue, Zhigang(3);Zhu, Xianmin(1,2);Zhang, Peng(2);Fan, Guoping(1,5). ONCOGENE. 2020. DOI:. 10.1038/s41388-020-01528-0

    33. Nuclear Morphological Remodeling in Human Granulocytes Is Linked to Prenylation Independently from Cytoskeleton. Martewicz, Sebastian(1);Luni, Camilla(1);Zhu, Xi(1,2,3);Cui, Meihua(1);Hu, Manli(1);Qu, Siqi(1,2);Buratto, Damiano(1);Yang, Guang(1);Grespan, Eleonora(4);Elvassore, Nicola(1,5,6,7). CELLS. 2020. DOI:. 10.3390/cells9112509

    34. Divinylsulfonamides enable the construction of homogeneous antibody–drug conjugates. Rong Huang(1,2);Yao Sheng(1);Ding Wei(1,2,3);Wenwen Lu(1,2);Hongli Chen(1);Biao Jiang(1). BIOORGANIC & MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.bmc.2020.115793

    35. Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Liu, Fengjiang(1,2,3);Liang, Jingxi(4);Zhang, Bing(1);Gao, Yan(1,5);Yang, Xiuna(1);Hu, Tianyu(1);Yang, Haitao(1);Xu, Wenqing(1);Guddat, Luke W.(6);Rao, Zihe(1,4,5,7). SCIENCE ADVANCES. 2020. DOI:. 10.1126/sciadv.abb9833

    36. Decision tree searching strategy to boost the identification of cross-linked peptides.. Huang, Rong(1,2);Gao, Xiuxia(1);Xu, Zili(1);Zhu, Wei(1);Wei, Ding(1,2);Jiang, Biao(1);Chen, Hongli(1);Chen, Wenzhang(1). ANALYTICAL CHEMISTRY. 2020. DOI:. 10.1021/acs.analchem.0c00452

    37. Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Meng, Bing(1);Lan, Keke(1,2);Xie, Jia(3);Lerner, Richard A.(3);Wilson, Ian A.(1,4,5);Yang, Bei(1). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020. DOI:. 10.1073/pnas.1918844117

    38. Conformable hyaluronic acid hydrogel delivers adipose-derived stem cells and promotes regeneration of burn injury. Dong, Yixiao(1,2,3);Cui, Meihua(1);Qu, Ju(1);Wang, Xuechun(1);Kwon, Sun Hyung(2);Barrera, Janos(2);Elvassore, Nicola(1);Gurtner, Geoffrey C.(2). ACTA BIOMATERIALIA. 2020. DOI:. 10.1016/j.actbio.2020.03.040

    39. Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance. Sun, Ning(1);Ren, Chaowei(1);Kong, Ying(5);Zhong, Hui(1,3);Chen, Jinju(5);Li, Yan(5);Zhang, Jianshui(5);Zhou, Yuedong(5);Qiu, Xing(2);Lin, Haifan(1,4);Song, Xiaoling(1);Yang, Xiaobao(1);Jiang, Biao(1,2). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.ejmech.2020.112190

    40. Iridium-catalyzed C-H amidation of s-tetrazines. Xiong, Huan(1);Gu, Yuang(1,2,3,4);Zhang, Shuning(1,2,3,4);Lu, Fengping(1);Ji, Qun(1);Liu, Lili(1);Ma, Peixiang(1);Yang, Guang(1);Hou, Wei(5,6);Xu, Hongtao(1). CHEMICAL COMMUNICATIONS. 2020. DOI:. 10.1039/d0cc01647k

    41. A Chemistry for Incorporation of Selenium into DNA-Encoded Libraries. Xu, Hongtao(1);Gu, Yuang(1,4,5,6);Zhang, Shuning(1,4,5,6);Xiong, Huan(1);Ma, Fei(1);Lu, Fengping(1);Ji, Qun(1);Liu, Lili(1);Ma, Peixiang(1);Hou, Wei(2,3);Yang, Guang(1);Lerner, Richard A.(7). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020. DOI:. 10.1002/anie.202003595

    42. Beyond Family: Modeling Non-hereditary Heart Diseases With Human Pluripotent Stem Cell-Derived Cardiomyocytes. Martewicz, Sebastian(1);Magnussen, Michael(2);Elvassore, Nicola(1,2,3,4). FRONTIERS IN PHYSIOLOGY. 2020. DOI:. 10.3389/fphys.2020.00384

    43. Bis(vinylsulfonyl)piperazines as efficient linkers for highly homogeneous antibody-drug conjugates. Huang, Rong(1,2);Sheng, Yao(1);Wei, Ding(1,2);Yu, Jianghui(1,2);Chen, Hongli(1);Jiang, Biao(1). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.ejmech.2020.112080

    44. A Synthetic Human Antibody Antagonizes IL-18R beta Signaling Through an Allosteric Mechanism. Liu, Shusu(1);Miersch, Shane(2);Li, Ping(1,3);Bai, Bingxin(1);Liu, Chunchun(1);Qin, Wenming(4);Su, Jie(1);Huang, Haiming(2,5);Pan, James(2);Sidhu, Sachdev S.(1,2);Wu, Donghui(1). JOURNAL OF MOLECULAR BIOLOGY. 2020. DOI:. 10.1016/j.jmb.2020.01.012

    45. Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cell Culture Prevents UVB-Induced Skin Aging in Human Keratinocytes and Dermal Fibroblasts. Li, Lu(1,2);Ngo, Hien T. T.(2);Hwang, Eunson(2);Wei, Xuan(1);Liu, Ying(2);Liu, Jia(1);Yi, Tae-Hoo(2). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020. DOI:. 10.3390/ijms21010049

    46. Rapid and sensitive detection of COVID-19 using CRISPR/Cas12a-based detection with naked eye readout, CRISPR/Cas12a-NER. Wang, Xinjie(1);Zhong, Mingtian(2);Liu, Yong(3,4);Ma, Peixiang(1);Dang, Lu(5);Meng, Qingzhou(5);Wan, Wenwei(6);Ma, Xiaodong(2);Liu, Jia(1);Yang, Guang(1);Yang, Zifeng(3);Huang, Xingxu(6);Liu, Ming(3). SCIENCE BULLETIN. 2020. DOI:. 10.1016/j.scib.2020.04.041

    47. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Chen, Xiaobo(1,2,3);Chen, Jiayue(1);Yan, Bing(1);Zhang, Wei(1);Guddat, Luke W.(4);Liu, Xiang(1);Rao, Zihe(1,2,3,5,6). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020. DOI:. 10.1073/pnas.2002835117

    48. A DNA-encoded library for the identification of natural product binders that modulate poly (ADP-ribose) polymerase 1, a validated anti-cancer target. Li, Jie(1,2,3,4);Li, Yu(1,2,3,4);Lu, Fengping(1);Liu, Lili(1);Ji, Qun(1);Song, Ke(1);Yin, Qianqian(1);Lerner, Richard A.(5);Yang, Guang(1);Xu, Hongtao(1);Ma, Peixiang(1). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020. DOI:. 10.1016/j.bbrc.2020.04.022

    49. Generation of an induced pluripotent stem cell line (SIAISi003-A) from a 79-year-old patient with Alzheimer's disease having APOE3/4 genetic background. Dai, Qiuting(1,2);Zhang, Wenxin(1,2);Guo, Jinghui(1,2);Di, Weihao(1,2);Zhao, Jian(1,2);Zhang, Bei(3);Wang, Ying(1). STEM CELL RESEARCH. 2020. DOI:. 10.1016/j.scr.2020.101949

    50. Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo. Tao, Pingdong(1,2,3,4);Kuang, Yuanyuan(1,2,3,4);Li, Yu(1,2,3,4);Li, Wenping(1,2,3,4);Gao, Zibei(2);Liu, Lili(1);Qiang, Min(1);Zha, Zhao(1);Fan, Kun(1,2,3,4);Ma, Peixiang(1);Friedman, Jeffrey M.(5);Yang, Guang(1);Lerner, Richard A.(6). ADVANCED SCIENCE. 2020. DOI:. 10.1002/advs.202000818

    51. A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice. Kuang, Yuanyua(1,2,3,4);Zorzi, Veronica(5,6);Buratto, Damiano(1);Ziraldo, Gaia(5,6);Mazzarda, Flavia(5,7);Peres, Chiara(5,8);Nardin, Chiara(5,8);Salvatore, Anna Maria(5);Chiani, Francesco(5);Scavizzi, Ferdinando(5);Raspa, Marcello(5);Qiang, Min(1);Chu, Youjun(1);Shi, Xiaojie(1);Li, Yu(1,2,3,4);Liu, Lili(1);Shi, Yaru(1);Zonta, Francesco(1);Yang, Guang(1);Lerner, Richard A.(1,9);Mammano, Fabio(1,5,8). EBIOMEDICINE. 2020. DOI:. 10.1016/j.ebiom.2020.102825

    52. Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides. Cui, Yan-ru(1,2,3,4);Wang, Shao-jie(1);Chen, Jun(5);Li, Jie(1,2,3,4);Chen, Wenzhang(1);Wang, Shuyue(1,2,3,4);Meng, Bing(1);Zhu, Wei(1);Zhang, Zhuhong(6);Yang, Bei(1);Jiang, Biao(1);Yang, Guang(1);Ma, Peixiang(1);Liu, Jia(1). GENOME BIOLOGY. 2020. DOI:. 10.1186/s13059-020-01956-x

    53. Parabrachial neuron types categorically encode thermoregulation variables during heat defense. Wen Z. Yang(1,2,3);Xiaosa Du(1,2,4,5);Wen Zhang(4);Cuicui Gao(1,2,4,5);Hengchang Xie(1,2,4,5);Yan Xiao(6,7);Xiaoning Jia(1,2);Jiashu Liu(1,2);Jianhui Xu(8);Xin Fu(1,2,4,5);Hongqing Tu(1,2,4,5);Xiaoyu Fu(1,2,4,5);Xinyan Ni(1,2);Miao He(9);Jiajun Yang(6,7);Hong Wang(10);Haitao Yang(1,2);Xiao-hong Xu(4);Wei L. Shen(1,2). SCIENCE ADVANCES. 2020. DOI:. 10.1126/sciadv.abb9414

    54. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. Yang, Xiaolin(1,2,3,8);Hu, Tianyu(1,2);Yang, Xiuna(1,2);Xu, Wenqing(1,2);Yang, Haitao(1,2);Guddat, Luke W.(7);Zhang, Bing(1,2);Rao, Zihe(1,2,4,5,6). JOURNAL OF MOLECULAR BIOLOGY. 2020. DOI:. 10.1016/j.jmb.2020.05.019

    55. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Wang, Quan(1,2);Wu, Jiqin(3);Wang, Haofeng(1,2,4);Gao, Yan(5);Liu, Qiaojie(3);Mu, An(6,7);Ji, Wenxin(6,7);Yan, Liming(5);Zhu, Yan(1,2);Zhu, Chen(1,2);Fang, Xiang(3,6);Yang, Xiaobao(1,2);Huang, Yucen(5);Gao, Hailong(6,7);Liu, Fengjiang(1,2);Ge, Ji(5);Sun, Qianqian(1,2);Yang, Xiuna(1,2);Xu, Wenqing(1,2);Liu, Zhijie(1,2);Yang, Haitao(1,2);Lou, Zhiyong(5);Jiang, Biao(1,2);Guddat, Luke W.(8);Gong, Peng(3);Rao, Zihe(1,2,5,7). CELL. 2020. DOI:. 10.1016/j.cell.2020.05.034

    56. Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Gao, Yan(1,2,3,4);Yan, Liming(1,2);Huang, Yucen(1,2);Liu, Fengjiang(3,4);Zhao, Yao(3,4);Cao, Lin(5,6);Wang, Tao(1,2);Sun, Qianqian(3,4);Ming, Zhenhua(7);Zhang, Lianqi(1,2);Ge, Ji(1,2);Zheng, Litao(1,2);Zhang, Ying(1,2);Wang, Haofeng(3,4,8);Zhu, Yan(3,4);Zhu, Chen(3,4);Hu, Tianyu(3,4);Hua, Tian(3,4);Zhang, Bing(3,4);Yang, Xiuna(3,4);Li, Jun(3,4);Yang, Haitao(3,4);Liu, Zhijie(3,4);Xu, Wenqing(3,4);Guddat, Luke W.(9);Wang, Quan(3,4);Lou, Zhiyong(1,2);Rao, Zihe(1,2,3,4,5,6,10). SCIENCE. 2020. DOI:. 10.1126/science.abb7498

    57. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Jin, Zhenming(1,2,3,4);Zhao, Yao(1,2);Sun, Yuan(5);Zhang, Bing(1,2);Wang, Haofeng(1,2,6);Wu, Yan(5);Zhu, Yan(1,2);Zhu, Chen(1,2);Hu, Tianyu(1,2);Du, Xiaoyu(1,2,3,4);Duan, Yinkai(1,2);Yu, Jing(1,2);Yang, Xiaobao(1,2);Yang, Xiuna(1,2);Yang, Kailin(7);Liu, Xiang(8);Guddat, Luke W.(9);Xiao, Gengfu(5);Zhang, Leike(5);Yang, Haitao(1,2);Rao, Zihe(1,2,3,4,8). NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2020. DOI:. 10.1038/s41594-020-0440-6

    58. Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors. Jin, Zhenming(1,2,3,4);Du, Xiaoyu(3,4);Xu, Yechun(5);Deng, Yongqiang(6);Liu, Meiqin(7);Zhao, Yao(1,2);Zhang, Bing(1,2);Li, Xiaofeng(6);Zhang, Leike(7);Peng, Chao(8);Duan, Yinkai(1,2);Yu, Jing(1,2);Wang, Lin(1,2);Yang, Kailin(9);Liu, Fengjiang(1,2);Jiang, Rendi(7);Yang, Xinglou(7);You, Tian(1,2);Liu, Xiaoce(1,2);Yang, Xiuna(1,2);Bai, Fang(1,2);Liu, Hong(5);Liu, Xiang(10);Guddat, Luke W.(11);Xu, Wenqing(1,2,8);Xiao, Gengfu(7);Qin, Chengfeng(6);Shi, Zhengli(7);Jiang, Hualiang(1,2,5);Rao, Zihe(1,2,3,4,10);Yang, Haitao(1,2). NATURE. 2020. DOI:. 10.1038/s41586-020-2223-y

    59. Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Zhang, Lu(1,2,3,4);Zhao, Yao(1,2,3,5,6);Gao, Yan(7);Wu, Lijie(1,2,3);Gao, Ruogu(6,8,9);Zhang, Qi(1,2,3);Wang, Yinan(1,2,3,6);Wu, Chengyao(1,2,3);Wu, Fangyu(4);Gurcha, Sudagar S.(10);Veerapen, Natacha(10);Batt, Sarah M.(10);Zhao, Wei(4);Qin, Ling(1,2,3,12);Yang, Xiuna(1,2,3);Wang, Manfu(1,2,3);Zhu, Yan(1,2,3);Zhang, Bing(1,2,3);Bi, Lijun(8,9);Zhang, Xian'en(8,9);Yang, Haitao(1,2,3);Guddat, Luke W.(11);Xu, Wenqing(1,2,3);Wang, Quan(1,2,3,8,9);Li, Jun(1,2,3);Besra, Gurdyal S.(10);Rao, Zihe(1,2,3,4,7,8,9). SCIENCE. 2020. DOI:. 10.1126/science.aba9102

    60. IP3 Receptor Plasticity Underlying Diverse Functions. Hamada, Kozo(1);Mikoshiba, Katsuhiko(1). ANNUAL REVIEW OF PHYSIOLOGY. 2020. DOI:. 10.1146/annurev-physiol-021119-034433

    61. Intellectual disability-associated geneftsj1is responsible for 2 '-O-methylation of specific tRNAs. Li, Jing(1,2);Wang, Yan-Nan(3);Xu, Bei-Si(4);Liu, Ya-Ping(5);Zhou, Mi(1);Long, Tao(1);Li, Hao(1);Dong, Han(1);Nie, Yan(3);Chen, Peng R.(5);Wang, En-Duo(1,2);Liu, Ru-Juan(2). EMBO REPORTS. 2020. DOI:. 10.15252/embr.202050095

    62. Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response. Wang, Xiao(1,2,3);Ding, Chengfeng(1,2,3);Yu, Wenxia(1,2,3);Wang, Ying(4);He, Siting(3,5);Yang, Bei(6);Xiong, Yi-Chun(4);Wei, Jia(4);Li, Jifang(1,2,3);Liang, Jiayi(1,2,3);Lu, Zongyang(1,2,3);Zhu, Wei(1);Wu, Jing(1);Zhou, Zhi(1);Huang, Xingxu(1,2);Liu, Zhen(5);Yang, Li(4);Chen, Jia(1,2). CELL REPORTS. 2020. DOI:. 10.1016/j.celrep.2020.107723

    63. Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs. Jing Li(1,2);Yan-Nan Wang(3);Bei-Si Xu(4);Ya-Ping Liu(5);Mi Zhou(1);Tao Long(1);Hao Li(1);Han Dong(1);Yan Nie(3);Peng R. Chen(5);En-Duo Wang(1,2);Ru-Juan Liu(2). EMBO REPORTS. 2020. DOI:. -

    64. Building vertically-structured, high-performance electrodes by interlayer-confined reactions in accordion-like, chemically expanded graphite. Dong, Lei(1,2,3,4,6);Zhang, Long(1,2);Lin, Shan(1,2,8);Chen, Zhongxin(3,4,5);Wang, Yannan(7);Zhao, Xiaoxu(3,4,5);Wu, Tianqi(1,2);Zhang, Jiajia(1,2);Liu, Wei(6);Lu, Hongbin(1,2);Loh, Kian Ping(3,4,5). NANO ENERGY. 2020. DOI:. 10.1016/j.nanoen.2020.104482



    2019

    1. Zhang B#, Li J#*, Yang X, Wu L, Zhang J, Yang Y, Zhao Y, Zhang L, Yang X, Yang X, Cheng X, Liu Z, Jiang B, Jiang H, Guddat LW, Yang H*, Rao Z*. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell. 2019 Jan 24. ISSN: 0092-8674;

    2. 201. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Research. 2019 Jan 10. ISSN:0305-1048;    

    3. Lu, Xiaoyun#;  Liu, Yuwan#;  Yang, Yiqun#;  Wang, Shanshan#;  Wang, Qian;  Wang, Xiya;  Yan, Zhihui;  Cheng, Jian;  Liu, Cui;  Yang, Xue;  Luo, Hao;  Yang, Sheng;  Gou, Junran;  Ye, Luzhen;  Lu, Lina;  Zhang, Zhidan;  Guo, Yu;  Nie, Yan;  Lin, Jianping;  Li, Sheng;  Tian, Chaoguang;  Cai, Tao;  Zhuo, Bingzhao;  Ma, Hongwu;  Wang, Wen;  Ma, Yanhe;  Liu, Yongjun*;  Li, Yin*;  Jiang, Huifeng*. Constructing a synthetic pathway for acetylcoenzyme A from one-carbon through enzyme design. Nature Communications. 2019 Mar 26. ISSN:2041-1723;  

    4. Wang Xinyu#; Pu Jiahua#; Liu Yi; Ba Fang; Cui Mengkui; Li Ke; Xie Yu; Nie Yan; Mi Qixi; Li Tao; Liu Lingli; Zhu Manzhou; Zhong Chao*. Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications. National Science Review. 2019 Jul 30. ISSN:2053-714X;    

    5. Wang, Yannan#;  Zhang, Fan;  Nie, Yan*;  Shang, Guijun*;  Zhang, Heqiao*. Structural analysis of Shigella flexneri bi-functional enzyme HisIE in histidine biosynthesis. Biochemical and Biophysical Research Communications. 2019 Aug 20. ISSN:0006-291X;    

    6. El Khattabi, Laila#;  Zhao, Haiyan#;  Kalchschmidt, Jens#;  Young, Natalie#;  Jung, Seolkyoung;  Van Blerkom, Peter;  Kieffer-Kwon, Philippe;  Kieffer-Kwon, Kyong-Rim;  Park, Solji;  Wang, Xiang;  Krebs, Jordan;  Tripathi, Subhash;  Sakabe, Noboru;  Sobreira, Debora R.;  Huang, Su-Chen;  Rao, Suhas S. P.;  Pruett, Nathanael;  Chauss, Daniel;  Sadler, Erica;  Lopez, Andrea;  Nobrega, Marcelo A.;  Aiden, Erez Lieberman;  Asturias, Francisco J.*;  Casellas, Rafael*. A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell. 2019 Aug 22. ISSN:0092-8674;   

    7. Zhang, Yu#; Zhang, Xuefei#; Ba, Zhaoqing; Liang, Zhuoyi; Dring, Edward W.; Hu, Hongli; Lou, Jiangman; Kyritsis, Nia; Zurita, Jeffrey; Shamim, Muhammad S.; Aiden, Aviva Presser; Aiden, Erez Lieberman; Alt, Frederick W*. The fundamental role of chromatin loop extrusion in physiological V(D)J recombination. Nature. 2019 Sep 11. ISSN:0028-0836;  

    8. Qiu, Xing#; Sun, Ning#; Kong, Ying; Li, Yan; Yang, Xiaobao*; Jiang, Biao* . Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Organic Letters. 2019 May 8. ISSN:1523-7060;  

    9. Zhao, Quanju1#; Ren, Chaowei#; Liu, Linyi#; Chen, Jinju; Shao, Yubao; Sun, Ning; Sun, Renhong; Kong, Ying; Ding, Xinyu; Zhang, Xianfang; Xu, Youwei; Yang, Bei; Yin, Qianqian*; Yang, Xiaobao*; Jiang, Biao*. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Journal of Medicinal Chemistry. 2019 Oct 2. ISSN:0022-2623;  

    10. Rong Huang, Zhihong Li, Jianghui Yu, Hongli Chen,* and Biao Jiang*. H2O?Regulated Chemoselectivity in Oxa-Versus Aza-Michael Reactions. Organic Letters. 2019 May 16. ISSN:1523-7060 ;  

    11. Rong Huang,# Wei Zhu,# Yue Wu,# Jiakang Chen, Jianghui Yu, Biao Jiang,* Hongli Chen * and Wenzhang Chen*. A novel mass spectrometry-cleavable, phosphatebased enrichable and multi-targeting protein cross-linker. Chemical Science. 2019 May 23. ISSN:1452-3981;  

    12. Zhenzhen Yang#, Eric K. Wafula, Gunjune Kim, Saima Shahid, Joel R. McNeal, Paula E. Ralph, Prakash R. Timilsena, Wen-bin Yu, Elizabeth A. Kelly, Huiting Zhang, Thomas Nate Person, Naomi S. Altman, Michael J. Axtell, James H. Westwood & Claude W. dePamphilis* . Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants. Nature plants. 2019 Jul 22. ISSN:2055026X;  

    13. Gagliano O#, Luni C#, Qin W, Bertin E, Torchio E, Galvanin S, Urciuolo A, Elvassore N*.. Microfluidic reprogramming to pluripotency of human somatic cells. Nat Prot. 2019. ISSN:1745-2473;  

    14. Martewicz S#, Luni C#, Serena E, Pavan P, Chen VH-S, Rampazzo A, Elvassore N*.. Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli. Ann Biomed Eng. 2019. ISSN:0090-6964 (Print) 1573-9686 (Online);  

    15. Giobbe GG#, Crowley C#, Luni C#, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Hu Q, Michielin F, Meran L, Urbani L, Manfredi A, van Son G, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N*, De Coppi P*. Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoid culture. Nat Commun. 2019 (in press). ISSN:2041-1723;  

    16. Wang Chen#, Yang Zhenzhen, Guo Fanghao, Shi Shuo, Han Xiaoshuai, Zeng An, Lin Haifan*, Jing Qing*. Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea. J Biol Chem. 2019 Jun 21. ISSN:0021-9258;  

    17. Xinying Xue#, Chen Wang#, Zhiqiang Xue#, Jiaxin Wen,Jun Han, Xidong Ma, Xuelei Zang, Hui Deng, Rui Guo, Idorenyin Polycarp Asuquo, Chong Qin, Haijiao Wang, Quansheng Gao*, Sanhong Liu*, Jianxin Wang*. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Acta Biochimica et Biophysica Sinica. 2019 Nov 15. ISSN:1672-9145;  

    18. Tonon F#, Giobbe GG#, Zambon A, Luni C, Gagliano O, Floreani A, Grassi G, Elvassore N*. In vitro metabolic zonation through oxygen gradient on a chip. Sci Rep. 2019. ISSN:2045-2322;  

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    20. Beninatto R#*, Barbera C, De Lucchi O, Borsato G, Serena E, Guarise C, Pavan M, Luni C, Martewicz S, Galesso D, Elvassore N*. Photocrosslinked hydrogels from coumarin derivatives of hyaluronic acid for tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2019. ISSN:0928-4931;  

    21. Wang M#, Guo X#, Yang X, Zhang B, Ren J, Liu A, Ran Y, Yan B, Chen F, Guddat LW, Hu J*, Li J* and Rao Z. Mycobacterial dynamin-like protein IniA mediates membrane fission. . Nat Commun. 2019 Aug 29. ISSN:2041-1723;

    22. Wang S#, Zhou K, Yang X, Zhang B, Zhao Y, Xiao Y, Yang X, Yang H, Guddat LW, Li J, Rao Z. LW, Li J*, Rao Z*. Structural insights into substrate recognition by the type VII secretion system..Protein & Cell. . 2019 Nov 23. ISSN:1674-8018;  

    23. Wang N#, Zhao D#, Wang J#, Zhang Y#, Wang M, Gao Y, Li F, Wang J, Bu Z*, Rao Z*, Wang X*. Architecture of African swine fever virus and implications for viral assembly. Science. 2019 Nov 1. ISSN:0033-3131;  

    24. Xia S#, Yan L#, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA*, Jiang S*, Yang B*, Lu L*. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science Advances. 2019 Apr 10. ISSN:2375-2548;  

    25. Pang X#, Tong Y, Xue W, Yang Y-F, Chen X, Liu J*, Chen D*. Expression and characterization of recombinant human lactoferrin in edible alga Chlamydomonas reinhardtii. Bioscience, Biotechnology, and Biochemistry. 2019 Jan 23. ISSN:0916-8451;  

    26. Li B#, Zhou X-H# Yang P-Y, Zhu L, Zhong Y, Cai Z, Jiang B, Cai X, Liu J*, Jiang X*. Photoactivatable Fluorogenic Labeling via Turn-On Click-Like Nitroso-Diene Bioorthogonal Reaction. Advanced Science. 2019 May 2. ISSN:2198-3844;  

    27. Pang X#, Tong Y, Li F, Wei X, Chen X*, Liu J*, Chen D*. Expression and characterization of human lactoferrin with tandem zinc finger protein in Chlamydomonas reinhardtii. Algal Research. 2019 Nov. ISSN:2211-9264;  

    28. Li L#, Ngo HTT, Hwang E, Wei X, Liu Y, Liu J*, Yi T-H*. Conditioned medium from human adipose-derived mesenchymal stem cell culture prevents UVB-induced skin aging in human keratinocytes and dermal fibroblasts. International Journal of Molecular Sciences. In press. ISSN:1422-0067;  

    29. Bian Hu#, Yan Zou, Linlin Zhang, Jiaxing Tang, Gabriele Niedermann, Elke Firat, Xingxu Huang*, and Xuekai Zhu*. Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells. Human Gene Therapy. 2019 Apr 10. ISSN:1557-7422;   

    30. Qinan Yin#, Jiaxing Tang, Xuekai Zhu*. Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer. Briefings in Functional Genomics. 2019 Mar 22. ISSN:2041-2657;  

    31. Shi X#, Xiao Z#, Zonta F, Wang W, Wan Y, Li Y, Wang N, Kuang Y, Du M, Dong J, Wang J, Yang G*. Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte. Stem Cells. 2019 Feb 28. ISSN:1066-5099;  

    32. Ma P#, Xu H#, Li J#, Lu F, Ma F, Wang S, Xiong H, Wang W, Buratto D, Zonta F, Wang N, Liu K, Hua T, Zhi-jie Liu, Yang G*, Lerner RA*. Functionality independent DNA encoding of complex natural products. Angew Chem Int Ed Engl. 2019 May 22. ISSN:1433-7851;  

    33. Liu Y, Zhang J, Wang R, Wu Y, Wang W, Xin X, Du M, Cao Y, Zhang H*. Identification of novel Kv1.3 targeting venom peptides by a single round of autocrine-based selection. Biochem Biophys Res Commun. 2019 Jan 14. ISSN:0006-291X;  

    34. Yang YQ, Liang J, Han XD, Tian RM, Liu XS, Mao W, Xu HT*, Liu B*, Xu P*. Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival. Biomed Pharmacother. 2019 Jan 14. ISSN:0753-3322;  

    35. Lu Y, Yan JS, Xia L, Qin K, Yin QQ, Xu HT, Gao MQ, Qu XN, Sun YT, Chen GQ. 2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia. Haematologica. 2019 Aug 3. ISSN:0390-6078;  

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    39. Yang Z, Wan Y, Tao P, Qiang M, Dong X, Lin CW, Yang G, Zheng T*, Lerner RA*. A cell-cell interaction format for selection of high-affinity antibodies to membrane proteins. Proc Natl Acad Sci U S A. 2019 Jul 23. ISSN:0027-8424;  

    40. Xu H#.Ma F#.Wang N.Hou W.Xiong H.Lu F, Li J.Wang S.Ma P.Yang G*.Lerner RA*.. DNA-Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On-DNA Suzuki, Sonogashira, and Buchwald Reactions. Advance Science. 2019 Sep 30. ISSN:2198-3844;  

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    43. W. Hou, H. Xiong, R. Bai, Z. Xiao, L. Su, B.H. Ruan*, H. Xu*. Synthesis of Indazolo[2,1-a]Cinnolines via Rhodium (III)-Catalyzed C–H activation/annulation under mild conditions. Tetrahedron. 2019 Jun 24. ISSN:0040-4020;  

    44. X. Wang, R. Tian, Y. Yang, Z.-Y. Lu, X. Han, X. Liu, W. Mao, P. Xu*, H. Xu*, B. Liu*. Triptriolide antagonizes triptolide-induced nephrocyte apoptosis via inhibiting oxidative stress in vitro and in vivo. Biomed Pharmacother. 2019 Jul 15. ISSN:0753-3322;  

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    47. Gaia Ziraldo#, Damiano Buratto#, Yuanyuan Kuang, Liang Xu, Andrea Carrer, Chiara Nardin, Francesco Chiani, Anna Maria Salvatore, Gaetano Paludetti, Richard A Lerner, Guang Yang*, Francesco Zonta*, Fabio Mammano*. A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function. Frontiers in physiology. 2019 Jun 11. ISSN:1664-042X

    48. Nielsen BS#, Zonta F, T Farkas, T Litman, MS Nielsen, N MacAulay*. Structural determinants underlying permeant discrimination of the Cx43 hemichannel. Journal of Biological Chemistry, 2019, 294 (45), 16789-16803

    49. Yang Zhang#, Xiaodan Sun#, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch, Sachdev S Sidhu*, Donghui Wu*. A potent anti-SpuE antibody allosterically inhibits type III secretion system and attenuates virulence of Pseudomonas aeruginosa. Journal of molecular biology, Volume 431, Issue 24, 6 December 2019, Pages 4882-4896


    2018
    1.

    Giulitti S, Pellegrini M, Zorzan I, Martini P, Gagliano O, Mutarelli M, Ziller MJ, Cacchiarelli D, Romualdi C, Elvassore N, Martello G. 2018. Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics. Nat Cell Biol. doi: 10.1038/s41556-018-0254-5.

    2.

    Zoso A., Zambon A., Gagliano O., Giulitti S., Prevedello L., Fadini G.P., Luni C.,Elvassore N. (2018) Cross-talk of healthy and impaired human tissues for dissection of disease pathogenesis. Biotechnol Progr. doi: 10.1002/btpr.2766.

    3.

    Martewicz S.*, Luni C.*, Serena E., Pavan P., Chen V. H.-S., Rampazzo A., Elvassore N. (2018) Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli. Ann Biomed Eng. doi: 10.1007/s10439-018-02134-8.

    4.

    Prevedello L., Michielin F., Balcon M., Savio E., Pavan P., Elvassore N. (2018) A novel microfluidic platform for biomechano-stimulations on a chip. Ann Biomed Eng.<.em> doi: 10.1007/s10439-018-02121-z.

    5.

    Dong, Y.; Rodrigues, M.; Kwon, S.H.; Li, X.; A, S.; Brett, E.A.; Elvassore, N.; Wang, W.; Gurtner, C.G.(2018) ‘Acceleration of diabetic wound regeneration using an in-situ-formed stem cell-based skin substitute’. Advanced Healthcare Materials, 7(17):e1800432. doi: 10.1002/adhm.201800432.

    6.

    Hu Q., Luni C., Elvassore N. (2018) Microfluidics for secretome analysis under enhanced endogenous signaling. Biochem Bioph Res Co 497(2):480-484 doi: 10.1016/j.bbrc.2018.02.025.

    7.

    Liu J*, Li J, Li J, Zhu L, Wang S-J, Wei X, Ma P-X* (2018) Delivery of superoxide dismutase using Cys2-His2 zinc-finger proteins. in Methods Mol Biol (Liu J Eds., Humana Press, Totowa) 1867, 113-123.

    8.

    Liu J*, Liang Y-J, Ren P-L, Gaj T (2018) Manufacturing and delivering genome-editing proteins. in Methods Mol Biol (Liu J Eds., Humana Press, Totowa) 1867, 253-273.

    9.

    ShanghaiTech Researchers Discover a New Electron Transfer Mechanism from a Mycobacterial Respiratory Supercomplex

    10.

    Lab of stem cell biology reveals the mechanism of Wnt/β-catenin signaling pathway activation in triple negative breast cancer

    11.

    Vicario, M., Zanni, G., Vallese, F., Santorelli, F., Grinzato, A., Cieri, D., Berto, F., Frizzarin, M., Lopreiato, R., Zonta, F., Ferro, S., Sandre, M, Marin, O., Ruzzene, M., Bertini, E., Zanotti, G., Brini, M., Calì, T., Carafoli, E., A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia. Neurobiology of Disease, Volume 115, July 2018, Pages 157-166. doi: 10.1016/j.nbd.2018.04.009

    12.

    Zonta,F., Buratto, D., Crispino, G., Carrer, A., Bruno, F., Yang, G.,Mammano, F.,* and Pantano, S.,*. Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans. Front. Mol. Neurosci., 31 May 2018. https://doi.org/10.3389/fnmol.2018.00170

    13.

    Yang, Z., Du, M., Wang, W., Xin, X., Ma, P., Zhang, H., Lerner, R. A., Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity. Protein engineering, design & selection : PEDS 2018. https://doi.org/10.1093/protein/gzy002

    14.

    Martewicz S, Gabrel G, Campesan M, Canton M, Di Lisa F, Elvassore N. Live Cell Imaging in Microfluidic Device Proves Resistance to Oxygen/Glucose Deprivation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Anal Chem. 2018 Apr 9. doi: 10.1021/acs.analchem.7b05347.

    2017
    1.

    Piao Z., Wang W., Wei Y., Zonta F., Wan C., Bai J., Wu S., Wang X., Fang J.*, Characterization of an acetohydroxy acid synthase mutant conferring tolerance to imidazolinone herbicides in rice (Oryza sativa). Planta, 2017 Nov 18. doi: 10.1007/s00425-017-2817-2

    2.

    Martewicz S., Serena E., Zatti S., Keller g., Elvassore N., (2017) Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance. Stem Cell Research, Volume 25, December 2017, Pages 107-114, https://doi.org/10.1016/j.scr.2017.10.011

    3.

    Crispino G., Galindo Ramirez F., Campioni M., Zorzi V., Praetorius M., Di Pasquale G., Chiorini J., Mammano F*., In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors. Scientific Reports, 7(1): 6567. DOI: 10.1038/s41598-017-06759-y PMID: 28779115 IF: 4,259 (2016)

    4.

    Zorzi V., Paciello F., Ziraldo G., Peres C., Mazzarda F., Nardin C., Pasquini M., Chiani F., Raspa M., Scavizzi F., Carrer A., Crispino G., Ciubotaru CD., Monyer H., Fetoni AR., Salvatore AM., Mammano F*., Mouse Panx1 is dispensable for hearing acquisition and auditory function. Frontiers in Molecular Neuroscience, 10, 298. Received: 02 Oct 2017; Accepted: 30 Oct 2017. In Press. DOI: doi: 10.3389/fnmol.2017.00379 IF: 5,076 (2016)

    5.

    Carrer A., Leparulo A., Crispino G., Ciubotaru CD., Marin O., Zonta F., Bortolozzi M., Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease. Hum Mol Genet. 2017 Oct 25. doi: 10.1093/hmg/ddx386. [Epub ahead of print] PMID: 29077882

    6.

    Mao D., Dr. Liang Y., Liu Y., Zhou X., Ma J., Prof. Jiang B.*, Prof. Liu J.*, Prof. Ma D.*, Acid-Labile Acyclic Cucurbit[n]uril Molecular Containers for Controlled Release - Angewandte Chemie International Edition DOI: 10.1002/anie.201707164

    7.

    Vicario M., Calì T., Cieri D., Vallese F., Bortolotto R., Lopreiato R., Zonta F., Nardella M., Micalizzi A., Lefeber D., Valente E., Bertini E., Zanotti G., Zanni G., Brini M., Carafoli E.. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, (in press). A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Diseasedoi: 10.1016/j.bbadis.2017.08.006

    8.

    Xu L., Carrer A., Zonta F., Ma P, Qu Z., Li S., Buratto D., Ceriani F., Crispino G., Zorzi V., Ziraldo G., Bruno F., Nardin C., Peres C., Mazzarda .F, Salvatore A., Raspa M., Scavizzi F., Chu Y, Xie S., Liao J., Liu X., Wang W., Wang S., Yang G., Lerner R. and Mammano F.. Design and characterization of a human monoclonal antibody that modulates mutant  connexin 26 hemichannels implicated in deafness and skin disorders. Front. Mol. Neurosci. | doi: 10.3389/fnmol.2017.00298

    9.

    Liu H., Saxena A., Sidhu S.S.*, and Wu D.H*. (2017) Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds. Front Immunol 8:38 doi: 10.3389/fimmu.2017.00038.

    10.

    Han Y.B., Chen L.Q., Li Z., Tan Y.M., Feng Y., and Yang G.Y. (2017) Structural insights into the broad substrate specificity of a novel Endo-glycoceramidase I belonging to a new subfamily of GH5 glycosidase. J Biol Chem  doi: 10.1074/jbc.M116.763821.

    2016
    1.

    Saxena A and Wu D.H*. (2016) Advances in Therapeutic Fc Engineering ? Modulation of IgG-Associated Effector Functions and Serum Half-life. Front. Immunol. 7:580. doi: 10.3389/fimmu.2016.00580

    2.

    Liu J. and Shui S.L. (2016) Delivery methods for site-specific nucleases: Achieving the full potential of therapeutic gene editing. J Control Release 244(Pt A):83-97 doi: 10.1016/j.jconrel.2016.11.014.

    3.

    Scattolini V., Luni C., Zambon A., Galvanin S., Gagliano O., Ciubotaru C.D., Avogaro A., Mammano F., Elvassore N., and Fadini G.P. (2016) Simvastatin Rapidly and Reversibly Inhibits Insulin Secretion in Intact Single-Islet Cultures. Diabetes Ther 7(4):679-693 doi: 10.1007/s13300-016-0210-y.

    4.

    Ceriani F., Pozzan T., and Mammano F. (2016) Critical role of ATP-induced ATP release for Ca2+ signaling in nonsensory cell networks of the developing cochlea. Proc Natl Acad Sci U S A 113(46):E7194-E7201 doi: 10.1073/pnas.1616061113.

    5.

    Cali T., Frizzarin M., Luoni L., Zonta F., Pantano S., Cruz C., Bonza M.C., Bertipaglia I., Ruzzene M., De Michelis M.I., Damiano N., Marin O., Zanni G., Zanotti G., Brini M., Lopreiato R., and Carafoli E. (2016) The ataxia related G1107D mutation of the plasma membrane Ca2+ ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process. Biochim Biophys Acta 1863(1):165-173 doi: 10.1016/j.bbadis.2016.09.007.

    6.

    Gaj T., Sirk S.J., Shui S.-l., and Liu J. (2016) Genome-Editing Technologies: Principles and Applications. Cold Spring Harbor Perspectives in Biology:a023754 doi: 10.1101/cshperspect.a023754.

    7.

    Orlandini E.*, Baiesi M., Zonta F. (2016) How Local Flexibility Affects Knot Positioning in Ring Polymers. Macromolecules (online)  doi: 10.1021/acs.macromol.6b00712.

    8.

    Wang W*, Ma P*, Dong H, Krause HJ, Zhang Y, Willbold D, Offenhaeusser A, Gu Z.(2016) A Magnetic Nanoparticles Relaxation Sensor for Protein-Protein Interaction Detection at Ultra-Low Magnetic Field. Biosens Bioelectron. 80:661-665. doi: 10.1016/j.bios.2016.02.037.

    9.

    Zhang H., Du M., Xie J., Liu X., Sun J., Wang W., Xin X., Possani L.D., Yea K., and Lerner R.A. (2016) Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angew Chem Int Ed Engl  doi: 10.1002/anie.201603052.

    10.

    Liu S.S., Wei X., Ji Q., Xin X., Jiang B*., and Liu J*. (2016) A facile and efficient transposon mutagenesis method for generation of multi-codon deletions in protein sequences. J Biotechnol 227:27-34 doi: 10.1016/j.jbiotec.2016.03.038.

    11.

    Gagliano O., Elvassore N., and Luni C. (2016) Microfluidic technology enhances the potential of human pluripotent stem cells. Biochem Biophys Res Commun  473(3):683-687 doi: 10.1016/j.bbrc.2015.12.058.

    12.

    Chen H., Han C., Wu J., Liu X., Zhan Y., Chen J., Chen Y., Gu R., Zhang L., Chen S., Jia J., Zhen X., Zheng L.T., and Jiang B. (2016) Accessible Method for the Development of Novel Sterol Analogues with Dipeptide-like Side Chains That Act as Neuroinflammation Inhibitors. ACS Chem Neurosci 7(3):305-315 doi: 10.1021/acschemneuro.5b00256.

    13.

    Wang Z., Liu N., Shi S., Liu S., and Lin H. (2016) The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer. J Biol Chem  doi: 10.1074/jbc.M116.723239.

    14.

    Peng J.C., Valouev A., Liu N., and Lin H. (2016) Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Nat Genet 48(3):283-291 doi: 10.1038/ng.3486.

    15.

    Folda A., Citta A., Scalcon V., Cali T., Zonta F., Scutari G., Bindoli A., and Rigobello M.P. (2016) Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State. Sci Rep 6:23071 doi: 10.1038/srep23071.

    2015
    1.
    Ge X.Q., Han J., Cheng E.C., Yamaguchi S., Shima N., Thomas J.L., and Lin H.F. (2015) Embryonic Stem Cells License a High Level of Dormant Origins to Protect the Genome against Replication Stress. Stem Cell Reports 5(2):185-194 doi: 10.1016/j.stemcr.2015.06.002.

    2.
    Gonzalez J., Qi H.Y., Liu N., and Lin H.F. (2015) Piwi Is a Key Regulator of Both Somatic and Germline Stem Cells in the Drosophila Testis. Cell Reports 12(1):150-161 doi: 10.1016/j.celrep.2015.06.004.

    3.
    Wu D., Kaan H.Y., Zheng X., Tang X., He Y., Vanessa Tan Q., Zhang N., and Song H. (2015) Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1. Sci Rep 5:14738 doi: 10.1038/srep14738.

    4.
    Yea K., Zhang H.K., Xie J., Jones T.M., Lin C.W., Francesconi W., Berton F., Fallahi M., Sauer K., and Lerner R.A. (2015) Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America 112(45):E6158-E6165 doi: 10.1073/pnas.1519079112.

    5.
    Liu J., Gaj T., Yang Y., Wang N., Shui S., Kim S., Kanchiswamy C.N., Kim J.S., and Barbas C.F., 3rd (2015) Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells. Nat Protoc 10(11):1842-1859 doi: 10.1038/nprot.2015.117.

    6.
    (Review article in Chinese) Pang X.N., Hong X., Wei X., Chen X.W., Liu J.*,  and  Chen D.F.*(2015). Research progress in physicochemical characteristics of lactoferrin and its recombinant expression systems. Hereditas (Beijing), 37(9): 873-884 doi: 10.16288/j.yczz.15-146  
     (庞晓楠, 弘笑, 魏璇, 陈喜文, 刘佳*, 陈德富*(2015). 乳铁蛋白的理化性质及其重组表达系统的研究进展. 遗传, 37(9): 873-884 doi: 10.16288/j.yczz.15-146)


    7.
    Sun Y., Liu J., Jiang X., Sun T., Liu L., Zhang X., Ding S., Li J., Zhuang Y., Wang Y., and Wang R. (2015) One-Step Synthesis of Chiral Oxindole-type Analogues with Potent Anti-inflammatory and Analgesic Activities. Sci Rep 5:13699 doi: 10.1038/srep13699.

    8.
    Liu S.S., Wei X., Dong X., Xu L., Liu J., and Jiang B. (2015) Structural plasticity of green fluorescent protein to amino acid deletions and fluorescence rescue by folding-enhancing mutations. BMC Biochem 16(1):17 doi: 10.1186/s12858-015-0046-5.

    9.
    Meyer P.A., Li S., Zhang M., Yamada K., Takagi Y., Hartzog G.A., and Fu J. (2015) Structures and functions of the multiple KOW domains of transcription elongation factor Spt5. Mol Cell Biol  doi: 10.1128/MCB.00520-15.

    10.
    Wu J., Du J., Gu R., Zhang L., Zhen X., Li Y., Chen H., Jiang B., and Zheng L. (2015) Inhibition of neuroinflammation by synthetic androstene derivatives incorporating amino acid methyl esters on activated BV-2 microglia. ChemMedChem 10(4):610-616 doi: 10.1002/cmdc.201500027.

    11.
    Cianci, M., Folli, C., Zonta, F., Florio, P., Berni, R. & Zanotti, G. (2015). Structural evidence for asymmetric ligand binding to transthyretin. Acta Cryst. D71 1582-1592 doi:10.1107/S1399004715010585.

    12.
    Yea K., Xie J., Zhang H., Zhang W., and Lerner R.A. (2015) Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic. Curr Opin Chem Biol 26C:1-7 doi: 10.1016/j.cbpa.2015.01.002.

    13.
    Liu J., Gaj T., Wallen M.C., and Barbas C.F., 3rd (2015) Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering. Mol Ther Nucleic Acids 4:e232 doi: 10.1038/mtna.2015.6.

    14.
    Gaj T. and Liu J. (2015) Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains. J Vis Exp (97) doi: 10.3791/52814.

    2014
    1.
    Xie J., Yea K., Zhang H., Moldt B., He L., Zhu J., and Lerner R.A. (2014) Prevention of cell death by antibodies selected from intracellular combinatorial libraries. Chem Biol 21(2):274-283 doi: 10.1016/j.chembiol.2013.12.006.

    2.
    Lin Y., Qiu Y., Xu C., Liu Q., Peng B., Kaufmann G.F., Chen X., Lan B., Wei C., Lu D., Zhang Y., Guo Y., Lu Z., Jiang B., Edgington T.S., and Guo F. (2014) Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis. J Natl Cancer Inst 106(4):dju012 doi: 10.1093/jnci/dju012.

    3.
    Zhao X., Qu Z., Tickner J., Xu J., Dai K., and Zhang X. (2014) The role of SATB2 in skeletogenesis and human disease. Cytokine Growth Factor Rev 25(1):35-44 doi: 10.1016/j.cytogfr.2013.12.010.

    4.
    Liu, J., Sun, Y., Zhang, X., Liang, X., Wu, Y., Wang, Y. and Jiang, X. (2014) Spirooxindoles, a potential novel class of anti-inflammatory agents. Inflamm. Cell Signal. 1: e372 doi: 10.14800/ics.372.

    2013
    1.
    Jiang B., Li M.M., Xing P., and Huang Z.G. (2013) A concise formal synthesis of (-)-hamigeran B. Org Lett 15(4):871-873 doi: 10.1021/ol400030a.

    2.
    Yea K., Zhang H., Xie J., Jones T.M., Yang G., Song B.D., and Lerner R.A. (2013) Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections. Proc Natl Acad Sci U S A 110(37):14966-14971 doi: 10.1073/pnas.1313671110.


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